File:Neristatin 1.svg
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Size of this PNG preview of this SVG file: 572 × 436 pixels. Other resolutions: 315 × 240 pixels | 630 × 480 pixels | 1,008 × 768 pixels | 1,280 × 976 pixels | 2,560 × 1,951 pixels.
Original file (SVG file, nominally 572 × 436 pixels, file size: 31 KB)
| Description |
English: Chemical structure of neristatin 1, a polyketide isolated from Bugula neritina. Ki for protein kinase C: 21.2 nM (PDBu: 0.53 nM). Absolute stereochemistries of northern hemisphere of neristatin were firstly assigned as 3(R), 5(R), 7(S), 9(S), and 15(R) based upon the known absolute stereochemistry of the related bryostatins, but X-ray crystal structure in the patent document indicates that absolute stereochemistry at position C-9 (hemiketal position) is R.
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| Date | ||||
| Source | Own work | |||
| Author | Charlesy | |||
| Permission (Reusing this file) |
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| Annotations | This image is annotated: View the annotations at Commons |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 00:31, 21 November 2017 | | 572 × 436 (31 KB) | Charlesy | Stereochemistry at C-9. |
| 07:58, 27 June 2012 |  | 465 × 362 (18 KB) | Charlesy | {{Information |Description ={{en|1=Chemical structure of neristatin 1, a polyketide isolated from ''Bugula neritina''. {{cite journal|title= Antineoplastic agents. 224. Isolation and structure of neristatin 1|author=Pettit, G. R.; Gao, F.; Herald,... |
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